CDRISK2: The Uganda Schistosomiasis Multidisciplinary Research Center (U-SMRC)
Project Period
January 2022 - December 2027
Project Partners
The main objective of the Uganda Schistosomiasis Multidisciplinary Research Centre (U-SMRC) is to develop a comprehensive understanding of the biological drivers of severe schistosomal morbidity. The project emphasizes a life-course perspective (from infection rates and evolution of schistosome-specific immune responses in pre-school-age children to risk factors for severe morbidity in adults); we capture each stage in the parasite life cycle (through investigation of the human host, parasites, and snails). The data will inform the development of a comprehensive, integrated model describing the drivers of severe schistosomal morbidity. This will enable us to explore the likely benefits of a range of strategies for the prevention and management of severe schistosomiasis, supporting the translation of findings to policy and practice. This work is conducted in communities along the shores of Lake Victoria and Lake Albert in Uganda.
Project Period: 5 years (2022-2027)
Project Funder: NIH (USA)
Project Team
Partners:
- Uganda Virus Research Institute
- MRC/UVRI
- LSHTM Uganda Research Unit
- Vector Control Division Ministry of Health, Uganda
- Makerere University
- Mbarara University
- London School of Hygiene & Tropical Medicine
- Liverpool School of Tropical Medicine
- University of Cambridge
- University of Glasgow
- Leiden University Medical Center, Netherlands
- Royal Museum of Central Africa, Belgium