Health Challenges and Systems

Infectious and Non-Communicable Diseases

Health is the backbone of a nation. Sub-Saharan Africa bears a disproportionate burden of ill-health, and health remains largely under-funded by many governments in the region. In 2010, HIV/AIDS claimed up to 1.2 million lives in sub-Saharan Africa and a further 22.9 million people, including 2.3 million children, were living with HIV/AIDS. The region is also now increasingly threatened by non-communicable diseases (NCDs) such as cancer, cardiovascular diseases, diabetes, and chronic obstructive respiratory disease.



Current Project


ALPHA HIV Contextual Analysis

Program: Health Challenges and Systems

This is a two and a half-year multi-site study that is being implemented in ten sites, across six countries in Africa (Uganda, Kenya, Tanzania, Malawi, Zimbabwe and South Africa), which comprise the ALPHA Network. ALPHA stands for Analyzing Longitudinal Population-based HIV/AIDS data on Africa.  The ALPHA Network, coordinated by the London School of Hygiene and Tropical Medicine since 2005, links existing African HIV cohort studies and conducts comparative studies and met-analyses of the demographic correlates and consequences of HIV infection.

The ALPHA network sites are conducting secondary analyses of their mortality data to determine how AIDS deaths are distributed on the care and treatment continuum: what proportions occur to undiagnosed persons, to persons diagnosed but untreated, or to current and past ART patients.

However, since national policies within the six countries form the basis for the services that are available to the HIV infected people, it is important to review the policies and to describe how they are implemented locally. Understanding the context of implementation of national HIV treatment policies in the six countries could contribute to explaining the incentives and barriers that people face in accessing effective treatment for HIV.


  • London School of Hygiene and Tropical Medicine
  • ALPHA Network

Project period

  • April 2013 to September 2015

Project Funders

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    www.gatesfoundation.org ...

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